For some unknown reason, an email from a Microsoft 365 Business tenant with a calendar invitation (ics file) was blocked by iCloud servers.
De sender also received a bounce back email with de following url: https://learn.microsoft.com/en-us/troubleshoot/exchange/email-delivery/ndr/fix-error-code-550-4-4-7-in-exchange-online
The strange part is that I have had contact for a very long time with this person and organization.